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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM62008
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM62008
Synonyms:
2-(p-anisoylamino)-4-(trifluoromethyl)benzoic acid | 2-[(4-methoxybenzoyl)amino]-4-(trifluoromethyl)benzoic acid | 2-[(4-methoxyphenyl)carbonylamino]-4-(trifluoromethyl)benzoic acid | 2-[[(4-methoxyphenyl)-oxomethyl]amino]-4-(trifluoromethyl)benzoic acid | KSC-6-290 | KUC105921N | cid_46245543
Type:
Small organic molecule
Emp. Form.:
C16H12F3NO4
Mol. Mass.:
339.266
SMILES:
COc1ccc(cc1)C(=O)Nc1cc(ccc1C(O)=O)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: