Reaction Details Report a problem with these data
Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM62011
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM62011
Synonyms:
2-(p-anisoylamino)-2-phenyl-acetic acid | 2-[(4-methoxybenzoyl)amino]-2-phenylacetic acid | 2-[(4-methoxyphenyl)carbonylamino]-2-phenyl-ethanoic acid | 2-[[(4-methoxyphenyl)-oxomethyl]amino]-2-phenylacetic acid | KSC-09-190 | KUC105924N | cid_6916060
Type:
Small organic molecule
Emp. Form.:
C16H15NO4
Mol. Mass.:
285.2946
SMILES:
COc1ccc(cc1)C(=O)NC(C(O)=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: