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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM62021
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM62021
Synonyms:
KSC-6-291 | KUC105990N | N-(3,5-difluoro-2-hydroxy-phenyl)-4-methoxy-benzamide | N-(3,5-difluoro-2-hydroxyphenyl)-4-methoxybenzamide | N-[3,5-bis(fluoranyl)-2-oxidanyl-phenyl]-4-methoxy-benzamide | cid_46839337
Type:
Small organic molecule
Emp. Form.:
C14H11F2NO3
Mol. Mass.:
279.2388
SMILES:
COc1ccc(cc1)C(=O)Nc1cc(F)cc(F)c1O
Structure:
Search PDB for entries with ligand similarity: