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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM62046
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM62046
Synonyms:
4-chloranyl-2-(oxan-4-ylcarbonylamino)benzoic acid | 4-chloro-2-(oxane-4-carbonylamino)benzoic acid | 4-chloro-2-(tetrahydropyran-4-carbonylamino)benzoic acid | 4-chloro-2-[[4-oxanyl(oxo)methyl]amino]benzoic acid | KSC-20-012 | KUC106462N | cid_28777638
Type:
Small organic molecule
Emp. Form.:
C13H14ClNO4
Mol. Mass.:
283.708
SMILES:
OC(=O)c1ccc(Cl)cc1NC(=O)C1CCOCC1
Structure:
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