Reaction Details Report a problem with these data
Target
Alkanal monooxygenase alpha chain
Ligand
BDBM65979
Substrate
n/a
Meas. Tech.
Luminescence Microorganism Dose Retest to Identify Inhibitors of the AI-2 Quorum Sensing System
EC50
24450±n/a nM
Citation
 PubChem, PC Luminescence Microorganism Dose Retest to Identify Inhibitors of the AI-2 Quorum Sensing System PubChem Bioassay (2010)[AID] 
Target
Name:
Alkanal monooxygenase alpha chain
Synonyms:
Bacterial luciferase alpha chain | LUXA_VIBHA | luxA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40139.12
Organism:
Vibrio harveyi
Description:
gi_126509
Residue:
355
Sequence:
MKFGNFLLTYQPPELSQTEVMKRLVNLGKASEGCGFDTVWLLEHHFTEFGLLGNPYVAAAHLLGATETLNVGTAAIVLPTAHPVRQAEDVNLLDQMSKGRFRFGICRGLYDKDFRVFGTDMDNSRALMDCWYDLMKEGFNEGYIAADNEHIKFPKIQLNPSAYTQGGAPVYVVAESASTTEWAAERGLPMILSWIINTHEKKAQLDLYNEVATEHGYDVTKIDHCLSYITSVDHDSNRAKDICRNFLGHWYDSYVNATKIFDDSDQTKGYDFNKGQWRDFVLKGHKDTNRRIDYSYEINPVGTPEECIAIIQQDIDATGIDNICCGFEANGSEEEIIASMKLFQSDVMPYLKEKQ
  
Inhibitor
Name:
BDBM65979
Synonyms:
1-methyl-N-[4-(trifluoromethoxy)phenyl]-1H-imidazole-4-sulfonamide | 1-methyl-N-[4-(trifluoromethoxy)phenyl]-4-imidazolesulfonamide | 1-methyl-N-[4-(trifluoromethoxy)phenyl]imidazole-4-sulfonamide | 1-methyl-N-[4-(trifluoromethyloxy)phenyl]imidazole-4-sulfonamide | MLS000673272 | SMR000314513 | cid_2821584
Type:
Small organic molecule
Emp. Form.:
C11H10F3N3O3S
Mol. Mass.:
321.276
SMILES:
Cn1cnc(c1)S(=O)(=O)Nc1ccc(OC(F)(F)F)cc1
Structure:
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