Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM52217
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
3965±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM52217
Synonyms:
(2Z)-2-(6-methoxy-3-methyl-1,3-benzothiazol-2-ylidene)-1-(4-pyridyl)ethanone | (2Z)-2-(6-methoxy-3-methyl-1,3-benzothiazol-2-ylidene)-1-pyridin-4-yl-ethanone | (2Z)-2-(6-methoxy-3-methyl-1,3-benzothiazol-2-ylidene)-1-pyridin-4-ylethanone | MLS000108146 | SMR000104108 | cid_2147354
Type:
Small organic molecule
Emp. Form.:
C16H14N2O2S
Mol. Mass.:
298.36
SMILES:
COc1ccc2N(C)\C(Sc2c1)=C\C(=O)c1ccncc1
Structure:
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