Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM64576
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
4424±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM64576
Synonyms:
(3Z)-5-ethyl-3-(2-oxidanylidene-2-thiophen-2-yl-ethylidene)-1H-indol-2-one | (3Z)-5-ethyl-3-(2-oxo-2-thiophen-2-ylethylidene)-1H-indol-2-one | (3Z)-5-ethyl-3-[2-keto-2-(2-thienyl)ethylidene]oxindole | 5-ethyl-3-[2-oxo-2-(2-thienyl)ethylidene]-1,3-dihydro-2H-indol-2-one | MLS000536892 | SMR000143539 | cid_977927
Type:
Small organic molecule
Emp. Form.:
C16H13NO2S
Mol. Mass.:
283.345
SMILES:
CCc1ccc2NC(=O)\C(=C/C(=O)c3cccs3)c2c1
Structure:
Search PDB for entries with ligand similarity: