Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM65985
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
14230±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM65985
Synonyms:
2-(4-morpholinyl)ethane-1,1,2-tricarboxylic acid triethyl ester | 2-morpholinoethane-1,1,2-tricarboxylic acid triethyl ester | MLS000540859 | SMR000125917 | cid_3812720 | triethyl 2-morpholin-4-ylethane-1,1,2-tricarboxylate | triethyl 2-morpholino-1,1,2-ethanetricarboxylate
Type:
Small organic molecule
Emp. Form.:
C15H25NO7
Mol. Mass.:
331.3615
SMILES:
CCOC(=O)C(C(C(=O)OCC)C(=O)OCC)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: