Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM65986
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
3177±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM65986
Synonyms:
2-(3-bromophenyl)-4-quinolinecarboxylic acid [2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-2-oxoethyl] ester | 2-(3-bromophenyl)cinchoninic acid [2-[4-(2-furoyl)piperazino]-2-keto-ethyl] ester | MLS000564139 | SMR000151689 | [2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl] 2-(3-bromophenyl)quinoline-4-carboxylate | [2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-2-oxidanylidene-ethyl] 2-(3-bromophenyl)quinoline-4-carboxylate | cid_2391688
Type:
Small organic molecule
Emp. Form.:
C27H22BrN3O5
Mol. Mass.:
548.385
SMILES:
Brc1cccc(c1)-c1cc(C(=O)OCC(=O)N2CCN(CC2)C(=O)c2ccco2)c2ccccc2n1
Structure:
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