Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM65988
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
980±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM65988
Synonyms:
1-(tert-butyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1-tert-butyl-3-(4-fluorophenyl)-4-pyrazolo[3,4-d]pyrimidinamine | 1-tert-butyl-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine | MLS000326584 | SMR000179224 | [1-tert-butyl-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amine | cid_1489656
Type:
Small organic molecule
Emp. Form.:
C15H16FN5
Mol. Mass.:
285.3194
SMILES:
CC(C)(C)n1nc(-c2ccc(F)cc2)c2c(N)ncnc12
Structure:
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