Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM62227
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
2504±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM62227
Synonyms:
5-(4-chlorophenyl)sulfonyl-N-phenyl-1,2,3-thiadiazole-4-carboxamide | 5-(4-chlorophenyl)sulfonyl-N-phenyl-4-thiadiazolecarboxamide | 5-(4-chlorophenyl)sulfonyl-N-phenyl-thiadiazole-4-carboxamide | 5-(4-chlorophenyl)sulfonyl-N-phenylthiadiazole-4-carboxamide | SR-01000687641 | SR-01000687641-2 | cid_2767048
Type:
Small organic molecule
Emp. Form.:
C15H10ClN3O3S2
Mol. Mass.:
379.841
SMILES:
Clc1ccc(cc1)S(=O)(=O)c1snnc1C(=O)Nc1ccccc1
Structure:
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