Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM50249
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
7493±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM50249
Synonyms:
2-chloro-N-(3,4-dimethylphenyl)-5-(2,5-dioxo-1-pyrrolyl)benzamide | 2-chloro-N-(3,4-dimethylphenyl)-5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzamide | 2-chloro-N-(3,4-dimethylphenyl)-5-(2,5-dioxopyrrol-1-yl)benzamide | 2-chloro-N-(3,4-dimethylphenyl)-5-maleimido-benzamide | 5-[2,5-bis(oxidanylidene)pyrrol-1-yl]-2-chloranyl-N-(3,4-dimethylphenyl)benzamide | MLS000584944 | SMR000207329 | cid_616498
Type:
Small organic molecule
Emp. Form.:
C19H15ClN2O3
Mol. Mass.:
354.787
SMILES:
Cc1ccc(NC(=O)c2cc(ccc2Cl)N2C(=O)C=CC2=O)cc1C |c:19|
Structure:
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