Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM61536
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
11200±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM61536
Synonyms:
2-chloranyl-4,4-dimethyl-3-oxidanylidene-N-phenyl-pentanamide | 2-chloro-3-keto-4,4-dimethyl-N-phenyl-valeramide | 2-chloro-4,4-dimethyl-3-oxo-N-phenylpentanamide | MLS000710931 | SMR000280697 | cid_3091421
Type:
Small organic molecule
Emp. Form.:
C13H16ClNO2
Mol. Mass.:
253.725
SMILES:
CC(C)(C)C(=O)C(Cl)C(=O)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: