Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66014
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
14910±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66014
Synonyms:
4-chloranyl-2-methyl-5-(phenylmethyl)sulfonyl-pyridazin-3-one | 4-chloro-2-methyl-5-(phenylmethyl)sulfonyl-3-pyridazinone | 5-(benzylsulfonyl)-4-chloro-2-methyl-2,3-dihydropyridazin-3-one | 5-benzylsulfonyl-4-chloro-2-methyl-pyridazin-3-one | 5-benzylsulfonyl-4-chloro-2-methylpyridazin-3-one | MLS000833721 | SMR000457242 | cid_2800260
Type:
Small organic molecule
Emp. Form.:
C12H11ClN2O3S
Mol. Mass.:
298.745
SMILES:
Cn1ncc(c(Cl)c1=O)S(=O)(=O)Cc1ccccc1
Structure:
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