Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66016
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
1190±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66016
Synonyms:
6-Fluoro-9-methyl-2-methylsulfanyl-9H-1,3,4,9-tetraaza-fluorene | 8-fluoranyl-5-methyl-3-methylsulfanyl-[1,2,4]triazino[5,6-b]indole | 8-fluoro-5-methyl-3-(methylthio)-[1,2,4]triazin[5,6-b]indole | 8-fluoro-5-methyl-3-(methylthio)-[1,2,4]triazino[5,6-b]indole | 8-fluoro-5-methyl-3-methylsulfanyl-[1,2,4]triazino[5,6-b]indole | MLS001205963 | SMR000523461 | cid_2990360
Type:
Small organic molecule
Emp. Form.:
C11H9FN4S
Mol. Mass.:
248.279
SMILES:
CSc1nnc2c3cc(F)ccc3n(C)c2n1
Structure:
Search PDB for entries with ligand similarity: