Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66017
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
1902±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66017
Synonyms:
2-chloranyl-N-(2,6-dimethylphenyl)-3-oxidanylidene-3-phenyl-propanamide | 2-chloro-N-(2,6-dimethylphenyl)-3-keto-3-phenyl-propionamide | 2-chloro-N-(2,6-dimethylphenyl)-3-oxo-3-phenylpropanamide | MLS001176107 | SMR000595561 | cid_4484064
Type:
Small organic molecule
Emp. Form.:
C17H16ClNO2
Mol. Mass.:
301.767
SMILES:
Cc1cccc(C)c1NC(=O)C(Cl)C(=O)c1ccccc1
Structure:
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