Reaction Details Report a problem with these data
Target
Ammonium transporter MEP2
Ligand
BDBM66024
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 based on MLPCN hits
EC50
3857±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
Ammonium transporter MEP2
Synonyms:
AMT2 | MEP2 | MEP2_YEAST
Type:
Enzyme Catalytic Domain
Mol. Mass.:
53401.07
Organism:
Saccharomyces cerevisiae
Description:
gi_1302091
Residue:
499
Sequence:
MSYNFTGTPTGEGTGGNSLTTDLNTQFDLANMGWIGVASAGVWIMVPGIGLLYSGLSRKKHALSLLWASMMASAVCIFQWFFWGYSLAFSHNTRGNGFIGTLEFFGFRNVLGAPSSVSSLPDILFAVYQGMFAAVTGALMLGGACERARLFPMMVFLFLWMTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKRNDPVTRKGMPKYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWYSIMSTNLAAACGGLTWMVIDYFRCGRKWTTVGLCSGIIAGLVGITPAAGFVPIWSAVVIGVVTGAGCNLAVDLKSLLRIDDGLDCYSIHGVGGCIGSVLTGIFAADYVNATAGSYISPIDGGWINHHYKQVGYQLAGICAALAWTVTVTSILLLTMNAIPFLKLRLSADEEELGTDAAQIGEFTYEESTAYIPEPIRSKTSAQMPPPHENIDDKIVGNTDAEKNSTPSDASSTKNTDHIV
  
Inhibitor
Name:
BDBM66024
Synonyms:
(7-chloranylquinolin-4-yl) azepane-1-carboxylate | (7-chloroquinolin-4-yl) azepane-1-carboxylate | 1-azepanecarboxylic acid (7-chloro-4-quinolinyl) ester | MLS000113626 | SMR000109522 | azepane-1-carboxylic acid (7-chloro-4-quinolyl) ester | cid_2928644
Type:
Small organic molecule
Emp. Form.:
C16H17ClN2O2
Mol. Mass.:
304.771
SMILES:
Clc1ccc2c(OC(=O)N3CCCCCC3)ccnc2c1
Structure:
Search PDB for entries with ligand similarity: