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Target
Ammonium transporter MEP2
Ligand
BDBM66018
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 based on MLPCN hits
EC50
1381±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
Ammonium transporter MEP2
Synonyms:
AMT2 | MEP2 | MEP2_YEAST
Type:
Enzyme Catalytic Domain
Mol. Mass.:
53401.07
Organism:
Saccharomyces cerevisiae
Description:
gi_1302091
Residue:
499
Sequence:
MSYNFTGTPTGEGTGGNSLTTDLNTQFDLANMGWIGVASAGVWIMVPGIGLLYSGLSRKKHALSLLWASMMASAVCIFQWFFWGYSLAFSHNTRGNGFIGTLEFFGFRNVLGAPSSVSSLPDILFAVYQGMFAAVTGALMLGGACERARLFPMMVFLFLWMTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKRNDPVTRKGMPKYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWYSIMSTNLAAACGGLTWMVIDYFRCGRKWTTVGLCSGIIAGLVGITPAAGFVPIWSAVVIGVVTGAGCNLAVDLKSLLRIDDGLDCYSIHGVGGCIGSVLTGIFAADYVNATAGSYISPIDGGWINHHYKQVGYQLAGICAALAWTVTVTSILLLTMNAIPFLKLRLSADEEELGTDAAQIGEFTYEESTAYIPEPIRSKTSAQMPPPHENIDDKIVGNTDAEKNSTPSDASSTKNTDHIV
  
Inhibitor
Name:
BDBM66018
Synonyms:
5-[[5-(4-chlorophenyl)-2-furanyl]methylidene]-1,3-diazinane-2,4,6-trione | 5-[[5-(4-chlorophenyl)-2-furyl]methylene]barbituric acid | 5-[[5-(4-chlorophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione | MLS000911614 | SMR000718285 | cid_2754564
Type:
Small organic molecule
Emp. Form.:
C15H9ClN2O4
Mol. Mass.:
316.696
SMILES:
Clc1ccc(cc1)-c1ccc(\[#6]=[#6]-2\[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-2=O)o1
Structure:
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