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Target
Vacuolar aminopeptidase 1
Ligand
BDBM66056
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits
EC50
28570±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
Vacuolar aminopeptidase 1
Synonyms:
AMPL_YEAST | APE1 | API | LAP4 | YSC1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57084.90
Organism:
Saccharomyces cerevisiae
Description:
gi_486173
Residue:
514
Sequence:
MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
  
Inhibitor
Name:
BDBM66056
Synonyms:
(E)-3-(4-chloranyl-3-nitro-phenyl)-1-pyridin-3-yl-prop-2-en-1-one | (E)-3-(4-chloro-3-nitro-phenyl)-1-(3-pyridyl)prop-2-en-1-one | (E)-3-(4-chloro-3-nitrophenyl)-1-(3-pyridinyl)-2-propen-1-one | (E)-3-(4-chloro-3-nitrophenyl)-1-pyridin-3-ylprop-2-en-1-one | MLS000390403 | SMR000255370 | cid_6213986
Type:
Small organic molecule
Emp. Form.:
C14H9ClN2O3
Mol. Mass.:
288.686
SMILES:
[O-][N+](=O)c1cc(\C=C\C(=O)c2cccnc2)ccc1Cl
Structure:
Search PDB for entries with ligand similarity: