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Target
Beta-lactamase
Ligand
BDBM66139
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase
IC50
>59640±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM66139
Synonyms:
3-[(E)-2-(5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)ethenyl]-5-methyl-4-nitro-1,2-oxazole | 3-[(E)-2-(5-ethoxy-2-methyl-2,3-dihydrobenzofuran-6-yl)ethenyl]-5-methyl-4-nitroisoxazole | 3-[(E)-2-(5-ethoxy-2-methyl-coumaran-6-yl)vinyl]-5-methyl-4-nitro-isoxazole | MLS001177254 | SMR000594896 | cid_16293812
Type:
Small organic molecule
Emp. Form.:
C17H18N2O5
Mol. Mass.:
330.3352
SMILES:
CCOc1cc2CC(C)Oc2cc1\C=C\c1noc(C)c1[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: