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Target
Beta-lactamase
Ligand
BDBM51241
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase
IC50
>59640±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29494.42
Organism:
Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Description:
gi_60115532
Residue:
269
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDGESGNYG
  
Inhibitor
Name:
BDBM51241
Synonyms:
MLS000332169 | N-[3-Cyano-1-(3-methoxy-propyl)-8-methyl-10-oxo-1,10-dihydro-1,9,10a-triaza-anthracen-(2Z)-ylidene]- benzamide | N-[3-cyano-1-(3-methoxypropyl)-10-methyl-5-oxidanylidene-dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]benzamide | N-[3-cyano-1-(3-methoxypropyl)-10-methyl-5-oxo-2-dipyrido[3,4-c:1',2'-f]pyrimidinylidene]benzamide | N-[3-cyano-1-(3-methoxypropyl)-10-methyl-5-oxodipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]benzamide | N-[3-cyano-5-keto-1-(3-methoxypropyl)-10-methyl-dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]benzamide | SMR000434912 | cid_1865064
Type:
Small organic molecule
Emp. Form.:
C24H21N5O3
Mol. Mass.:
427.4552
SMILES:
COCCCn1c2nc3c(C)cccn3c(=O)c2cc(C#N)\c1=N/C(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: