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Target
Beta-lactamase
Ligand
BDBM53032
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase
IC50
>59640±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29494.42
Organism:
Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Description:
gi_60115532
Residue:
269
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDGESGNYG
  
Inhibitor
Name:
BDBM53032
Synonyms:
(5E)-5-[4-(dimethylamino)benzylidene]-3-methyl-2-thioxo-oxazolidin-4-one | (5E)-5-[[4-(dimethylamino)phenyl]methylidene]-3-methyl-2-sulfanylidene-1,3-oxazolidin-4-one | (5E)-5-[[4-(dimethylamino)phenyl]methylidene]-3-methyl-2-sulfanylidene-4-oxazolidinone | 5-[4-(dimethylamino)benzylidene]-3-methyl-2-thioxo-1,3-oxazolidin-4-one | MLS001008595 | SMR000495844 | cid_2259994
Type:
Small organic molecule
Emp. Form.:
C13H14N2O2S
Mol. Mass.:
262.327
SMILES:
CN(C)c1ccc(\C=C2\OC(=S)N(C)C2=O)cc1
Structure:
Search PDB for entries with ligand similarity: