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Target
Beta-lactamase
Ligand
BDBM51123
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase
IC50
37057±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | metallo-beta-lactamase IMP-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27125.88
Organism:
Pseudomonas aeruginosa
Description:
gi_27368096
Residue:
246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPSKPSN
  
Inhibitor
Name:
BDBM51123
Synonyms:
1-(4-nitro-2,1,3-benzoxadiazol-7-yl)-3-piperidinecarboxylic acid ethyl ester | 1-(7-nitrobenzofurazan-4-yl)nipecotic acid ethyl ester | MLS000729233 | SMR000307511 | cid_4871598 | ethyl 1-(4-nitro-2,1,3-benzoxadiazol-7-yl)piperidine-3-carboxylate | ethyl 1-(7-nitro-2,1,3-benzoxadiazol-4-yl)piperidine-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C14H16N4O5
Mol. Mass.:
320.3006
SMILES:
CCOC(=O)C1CCCN(C1)c1ccc([N+]([O-])=O)c2nonc12
Structure:
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