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Target
Beta-lactamase
Ligand
BDBM66131
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase
IC50
11277±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | metallo-beta-lactamase IMP-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27125.88
Organism:
Pseudomonas aeruginosa
Description:
gi_27368096
Residue:
246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPSKPSN
  
Inhibitor
Name:
BDBM66131
Synonyms:
6-Amino-2-ethyl-benzo[de]isoquinoline-1,3-dione | 6-amino-2-ethyl-benzo[de]isoquinoline-1,3-quinone | 6-amino-2-ethylbenzo[de]isoquinoline-1,3-dione | 6-azanyl-2-ethyl-benzo[de]isoquinoline-1,3-dione | MLS001210610 | SMR000513442 | cid_3099740
Type:
Small organic molecule
Emp. Form.:
C14H12N2O2
Mol. Mass.:
240.2573
SMILES:
CCN1C(=O)c2cccc3c(N)ccc(C1=O)c23
Structure:
Search PDB for entries with ligand similarity: