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Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM42988
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)
IC50
>39841±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM42988
Synonyms:
2-ethyl-N-(4-methylphenyl)-5-thieno[2,3-b]thiophenecarboxamide | 2-ethyl-N-(4-methylphenyl)thieno[2,3-b]thiophene-5-carboxamide | 2-ethyl-N-(p-tolyl)thieno[2,3-b]thiophene-5-carboxamide | 5-ethyl-N-(4-methylphenyl)thieno[2,3-b]thiophene-2-carboxamide | MLS000549172 | SMR000114651 | cid_902244
Type:
Small organic molecule
Emp. Form.:
C16H15NOS2
Mol. Mass.:
301.426
SMILES:
CCc1cc2cc(sc2s1)C(=O)Nc1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity: