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Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM43613
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)
IC50
32959±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM43613
Synonyms:
2-amino-4-(4-chlorophenyl)-6-methyl-3-pyridinecarbonitrile | 2-amino-4-(4-chlorophenyl)-6-methyl-nicotinonitrile | 2-amino-4-(4-chlorophenyl)-6-methylnicotinonitrile | 2-amino-4-(4-chlorophenyl)-6-methylpyridine-3-carbonitrile | 2-azanyl-4-(4-chlorophenyl)-6-methyl-pyridine-3-carbonitrile | MLS000533080 | SMR000140518 | cid_743778
Type:
Small organic molecule
Emp. Form.:
C13H10ClN3
Mol. Mass.:
243.692
SMILES:
Cc1cc(-c2ccc(Cl)cc2)c(C#N)c(N)n1
Structure:
Search PDB for entries with ligand similarity: