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Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM53349
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)
IC50
>39841±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM53349
Synonyms:
3-(1-benzofuran-2-carbonyl)-4-hydroxy-1-(5-methyl-1,2-oxazol-3-yl)-2-(3-prop-2-enoxyphenyl)-2H-pyrrol-5-one | 3-(1-benzofuran-2-ylcarbonyl)-1-(5-methyl-1,2-oxazol-3-yl)-4-oxidanyl-2-(3-prop-2-enoxyphenyl)-2H-pyrrol-5-one | 3-[2-benzofuranyl(oxo)methyl]-4-hydroxy-1-(5-methyl-3-isoxazolyl)-2-(3-prop-2-enoxyphenyl)-2H-pyrrol-5-one | 5-(3-allyloxyphenyl)-4-(benzofuran-2-carbonyl)-3-hydroxy-1-(5-methylisoxazol-3-yl)-3-pyrrolin-2-one | MLS001142995 | SMR000647543 | cid_3833515
Type:
Small organic molecule
Emp. Form.:
C26H20N2O6
Mol. Mass.:
456.4468
SMILES:
Cc1cc(no1)N1C(C(C(=O)c2cc3ccccc3o2)C(=O)C1=O)c1cccc(OCC=C)c1
Structure:
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