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Target
Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1)
Ligand
BDBM66172
Substrate
n/a
Meas. Tech.
Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)
IC50
1580±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3): TR-FRET-based biochemical high throughput dose response assay to identify agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2) PubChem Bioassay (2010)[AID] 
Target
Name:
Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1)
Synonyms:
CTG26 | NCOR2 | NCOR2_HUMAN | Nuclear receptor corepressor 2 (TRAC-1) | nuclear receptor corepressor 2 isoform 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
81401.89
Organism:
Homo sapiens (Human)
Description:
Q9Y618-2 gi_116256445
Residue:
766
Sequence:
MAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
  
Inhibitor
Name:
BDBM66172
Synonyms:
6-bromo-2-(2-furyl)-4-quinolinecarboxylic acid | MLS000705831 | SMR000227358 | cid_23672178 | potassium;6-bromanyl-2-(furan-2-yl)quinoline-4-carboxylate | potassium;6-bromo-2-(2-furanyl)-4-quinolinecarboxylate | potassium;6-bromo-2-(2-furyl)cinchoninate | potassium;6-bromo-2-(furan-2-yl)quinoline-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C14H7BrNO3
Mol. Mass.:
317.115
SMILES:
[O-]C(=O)c1cc(nc2ccc(Br)cc12)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: