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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67093
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67093
Synonyms:
3-[4-(4-methylpiperazin-1-yl)carbonylphenyl]-2-sulfanylidene-1H-quinazolin-4-one | 3-[4-(4-methylpiperazine-1-carbonyl)phenyl]-2-sulfanylidene-1H-quinazolin-4-one | 3-[4-(4-methylpiperazine-1-carbonyl)phenyl]-2-thioxo-1H-quinazolin-4-one | 3-[4-[(4-methyl-1-piperazinyl)-oxomethyl]phenyl]-2-sulfanylidene-1H-quinazolin-4-one | SR-01000556717-2 | cid_4381923
Type:
Small organic molecule
Emp. Form.:
C20H20N4O2S
Mol. Mass.:
380.463
SMILES:
CN1CCN(CC1)C(=O)c1ccc(cc1)-n1c(=S)[nH]c2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: