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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67102
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67102
Synonyms:
2-[4-(2,5-dimethylphenyl)sulfonyl-1-piperazinyl]-N-(4-fluorophenyl)-2-phenylacetamide | 2-[4-(2,5-dimethylphenyl)sulfonylpiperazin-1-yl]-N-(4-fluorophenyl)-2-phenyl-ethanamide | 2-[4-(2,5-dimethylphenyl)sulfonylpiperazin-1-yl]-N-(4-fluorophenyl)-2-phenylacetamide | 2-[4-(2,5-dimethylphenyl)sulfonylpiperazino]-N-(4-fluorophenyl)-2-phenyl-acetamide | SR-01000706676-2 | cid_15945404
Type:
Small organic molecule
Emp. Form.:
C26H28FN3O3S
Mol. Mass.:
481.582
SMILES:
Cc1ccc(C)c(c1)S(=O)(=O)N1CCN(CC1)C(C(=O)Nc1ccc(F)cc1)c1ccccc1
Structure:
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