Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67108
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67108
Synonyms:
N-(3-methoxyphenyl)-2-[4-(4-methylphenyl)sulfonyl-1-piperazinyl]-2-phenylacetamide | N-(3-methoxyphenyl)-2-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]-2-phenyl-ethanamide | N-(3-methoxyphenyl)-2-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]-2-phenylacetamide | N-(3-methoxyphenyl)-2-phenyl-2-(4-tosylpiperazino)acetamide | SR-03000000777-1 | cid_4879375
Type:
Small organic molecule
Emp. Form.:
C26H29N3O4S
Mol. Mass.:
479.591
SMILES:
COc1cccc(NC(=O)C(N2CCN(CC2)S(=O)(=O)c2ccc(C)cc2)c2ccccc2)c1
Structure:
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