Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67118
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67118
Synonyms:
4-[4-[2-(4-fluoroanilino)-2-keto-1-phenyl-ethyl]piperazino]sulfonylbenzamide | 4-[4-[2-(4-fluoroanilino)-2-oxo-1-phenylethyl]piperazin-1-yl]sulfonylbenzamide | 4-[4-[2-[(4-fluorophenyl)amino]-2-oxidanylidene-1-phenyl-ethyl]piperazin-1-yl]sulfonylbenzamide | 4-[[4-[2-(4-fluoroanilino)-2-oxo-1-phenylethyl]-1-piperazinyl]sulfonyl]benzamide | SR-03000000787-1 | cid_25181294
Type:
Small organic molecule
Emp. Form.:
C25H25FN4O4S
Mol. Mass.:
496.554
SMILES:
NC(=O)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C(=O)Nc1ccc(F)cc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: