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Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM32108
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
6115±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM32108
Synonyms:
6-keto-7,8,9,10-tetrahydrophenothiazine-3-carboxylic acid methyl ester | 6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxylic acid methyl ester | MLS000100349 | SMR000082651 | cid_1258835 | methyl 4-oxo-2,3,4,10-tetrahydro-1H-phenothiazine-7-carboxylate | methyl 6-oxidanylidene-7,8,9,10-tetrahydrophenothiazine-3-carboxylate | methyl 6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C14H13NO3S
Mol. Mass.:
275.323
SMILES:
COC(=O)c1ccc2N=C3CCCC(=O)C3Sc2c1 |t:8|
Structure:
Search PDB for entries with ligand similarity: