Reaction Details Report a problem with these data
Target
NADPH oxidase 1
Ligand
BDBM67455
Substrate
n/a
Meas. Tech.
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs
IC50
>17000±n/a nM
Citation
 PubChem, PC Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM67455
Synonyms:
(3,5-dichloro-4-pyridyl)-[(E)-(2,3,4-trimethoxybenzylidene)amino]amine | 3,5-bis(chloranyl)-N-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]pyridin-4-amine | 3,5-dichloro-N-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]-4-pyridinamine | 3,5-dichloro-N-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]pyridin-4-amine | SR-01000142982-2 | cid_9681005
Type:
Small organic molecule
Emp. Form.:
C15H15Cl2N3O3
Mol. Mass.:
356.204
SMILES:
COc1ccc(CN=Nc2c(Cl)cncc2Cl)c(OC)c1OC |w:7.6|
Structure:
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