Reaction Details Report a problem with these data
Target
NADPH oxidase 1
Ligand
BDBM67482
Substrate
n/a
Meas. Tech.
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs
IC50
>17000±n/a nM
Citation
 PubChem, PC Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM67482
Synonyms:
2-hydroxy-N-[4-[(4-phenylmethoxyphenyl)carbamoylamino]phenyl]benzamide | 2-hydroxy-N-[4-[[oxo-(4-phenylmethoxyanilino)methyl]amino]phenyl]benzamide | 2-oxidanyl-N-[4-[(4-phenylmethoxyphenyl)carbamoylamino]phenyl]benzamide | N-[4-[(4-benzoxyphenyl)carbamoylamino]phenyl]-2-hydroxy-benzamide | SR-03000000703-1 | cid_2813936
Type:
Small organic molecule
Emp. Form.:
C27H23N3O4
Mol. Mass.:
453.4892
SMILES:
Oc1ccccc1C(=O)Nc1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: