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Target
NADPH oxidase 1
Ligand
BDBM67560
Substrate
n/a
Meas. Tech.
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2
IC50
>17000±n/a nM
Citation
 PubChem, PC Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2 PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM67560
Synonyms:
1-(2,3,5,6-tetrafluoro-4-pyridinyl)-2-[1-[4-(1,2,4-triazol-1-yl)phenyl]ethenyl]hydrazine | 1-(2,3,5,6-tetrafluoro-4-pyridyl)-2-[1-[4-(1,2,4-triazol-1-yl)phenyl]vinyl]hydrazine | 1-(2,3,5,6-tetrafluoropyridin-4-yl)-2-[1-[4-(1,2,4-triazol-1-yl)phenyl]ethenyl]hydrazine | 1-[2,3,5,6-tetrakis(fluoranyl)pyridin-4-yl]-2-[1-[4-(1,2,4-triazol-1-yl)phenyl]ethenyl]diazane | SR-03000000894-1 | cid_44251534
Type:
Small organic molecule
Emp. Form.:
C15H10F4N6
Mol. Mass.:
350.2737
SMILES:
CC(N=Nc1c(F)c(F)nc(F)c1F)c1ccc(cc1)-n1cncn1 |w:2.1|
Structure:
Search PDB for entries with ligand similarity: