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Target
NADPH oxidase 1
Ligand
BDBM67561
Substrate
n/a
Meas. Tech.
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2
IC50
>17000±n/a nM
Citation
 PubChem, PC Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2 PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM67561
Synonyms:
6-fluoranyl-3-[2-[2,3,5,6-tetrakis(fluoranyl)pyridin-4-yl]hydrazinyl]indol-2-one | 6-fluoro-3-[(2,3,5,6-tetrafluoro-4-pyridinyl)hydrazo]-2-indolone | 6-fluoro-3-[2-(2,3,5,6-tetrafluoropyridin-4-yl)hydrazinyl]indol-2-one | 6-fluoro-3-[N'-(2,3,5,6-tetrafluoro-4-pyridyl)hydrazino]indol-2-one | SR-03000000895-1 | cid_8860824
Type:
Small organic molecule
Emp. Form.:
C13H5F5N4O
Mol. Mass.:
328.197
SMILES:
Fc1ccc2=C(NNc3c(F)c(F)nc(F)c3F)C(=O)N=c2c1 |c:4,21|
Structure:
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