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TargetNADPH oxidase 1
LigandBDBM67563
Substrate/Competitorn/a
Meas. Tech.Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2
IC50 3509±n/a nM
Citation PubChem, PC Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2 PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
NADPH oxidase 1
Name:NADPH oxidase 1
Synonyms:MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1
Type:PROTEIN
Mol. Mass.:64890.44
Organism:Homo sapiens (Human)
Description:ChEMBL_792877
Residue:564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCL
NFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHL
FNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVI
MTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHP
RKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKV
VMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGD
WTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYK
FQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSN
IVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSL
RKCCHRYSSLDPRKVQFYFNKENF
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BDBM67563
NameBDBM67563
Synonyms:1-(4-chloranyl-2-methyl-phenyl)-3-[(4-chloranyl-2-methyl-phenyl)carbamothioylamino]thiourea | 1-(4-chloro-2-methyl-phenyl)-3-[(4-chloro-2-methyl-phenyl)thiocarbamoylamino]thiourea | 1-(4-chloro-2-methylphenyl)-3-[(4-chloro-2-methylphenyl)carbamothioylamino]thiourea | 1-[[(4-chloro-2-methylanilino)-sulfanylidenemethyl]amino]-3-(4-chloro-2-methylphenyl)thiourea | SR-03000000897-1 | cid_17133004
TypeSmall organic molecule
Emp. Form.C16H16Cl2N4S2
Mol. Mass.399.361
SMILESCc1cc(Cl)ccc1NC(=S)NNC(=S)Nc1ccc(Cl)cc1C
Structure
n/a