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Target
NADPH oxidase 1
Ligand
BDBM67563
Substrate
n/a
Meas. Tech.
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2
IC50
3509±n/a nM
Citation
 PubChem, PC Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2 PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM67563
Synonyms:
1-(4-chloranyl-2-methyl-phenyl)-3-[(4-chloranyl-2-methyl-phenyl)carbamothioylamino]thiourea | 1-(4-chloro-2-methyl-phenyl)-3-[(4-chloro-2-methyl-phenyl)thiocarbamoylamino]thiourea | 1-(4-chloro-2-methylphenyl)-3-[(4-chloro-2-methylphenyl)carbamothioylamino]thiourea | 1-[[(4-chloro-2-methylanilino)-sulfanylidenemethyl]amino]-3-(4-chloro-2-methylphenyl)thiourea | SR-03000000897-1 | cid_17133004
Type:
Small organic molecule
Emp. Form.:
C16H16Cl2N4S2
Mol. Mass.:
399.361
SMILES:
Cc1cc(Cl)ccc1NC(=S)NNC(=S)Nc1ccc(Cl)cc1C
Structure:
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