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Target
Serine/threonine-protein kinase 33
Ligand
BDBM67571
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
>120000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM67571
Synonyms:
2-[5-[[2-(4-methylphenoxy)-1-oxoethyl]amino]-1,3,4-thiadiazol-2-yl]acetic acid ethyl ester | 2-[5-[[2-(4-methylphenoxy)acetyl]amino]-1,3,4-thiadiazol-2-yl]acetic acid ethyl ester | MLS000082525 | SMR000046348 | cid_665231 | ethyl 2-[5-[2-(4-methylphenoxy)ethanoylamino]-1,3,4-thiadiazol-2-yl]ethanoate | ethyl 2-[5-[[2-(4-methylphenoxy)acetyl]amino]-1,3,4-thiadiazol-2-yl]acetate
Type:
Small organic molecule
Emp. Form.:
C15H17N3O4S
Mol. Mass.:
335.378
SMILES:
CCOC(=O)Cc1nnc(NC(=O)COc2ccc(C)cc2)s1
Structure:
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