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TargetGuanine nucleotide-binding protein G(o), alpha subunit 1
LigandBDBM47776
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao with additional round of SAR compounds
EC50>30000±0 nM
Citation PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao with additional round of SAR compounds PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Guanine nucleotide-binding protein G(o), alpha subunit 1
Name:Guanine nucleotide-binding protein G(o), alpha subunit 1
Synonyms:guanine nucleotide-binding protein G(o) subunit alpha isoform a
Type:PROTEIN
Mol. Mass.:40043.59
Organism:Homo sapiens (Human)
Description:ChEMBL_321106
Residue:354
Sequence:
MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
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  Blast E-value cutoff:
BDBM47776
NameBDBM47776
Synonyms:3-chloranyl-N-(3-morpholin-4-ylpropyl)-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-N-(3-morpholin-4-ylpropyl)-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-N-(3-morpholinopropyl)-6-nitro-benzothiophene-2-carboxamide | 3-chloro-N-[3-(4-morpholinyl)propyl]-6-nitro-1-benzothiophene-2-carboxamide | MLS000684370 | SMR000295947 | cid_2225472
TypeSmall organic molecule
Emp. Form.C16H18ClN3O4S
Mol. Mass.383.85
SMILES[O-][N+](=O)c1ccc2c(Cl)c(sc2c1)C(=O)NCCCN1CCOCC1
Structure
n/a