Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM68321
Substrate
n/a
Meas. Tech.
SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM68321
Synonyms:
4-ethyl-N-(2-methoxy-5-morpholin-4-ylsulfonyl-phenyl)-5-methyl-thiophene-2-carboxamide | 4-ethyl-N-(2-methoxy-5-morpholin-4-ylsulfonylphenyl)-5-methylthiophene-2-carboxamide | 4-ethyl-N-(2-methoxy-5-morpholinosulfonyl-phenyl)-5-methyl-thiophene-2-carboxamide | 4-ethyl-N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]-5-methyl-2-thiophenecarboxamide | MLS-0435544.0001 | cid_26848739
Type:
Small organic molecule
Emp. Form.:
C19H24N2O5S2
Mol. Mass.:
424.534
SMILES:
CCc1cc(sc1C)C(=O)Nc1cc(ccc1OC)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: