Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM61037
Substrate
n/a
Meas. Tech.
SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2
EC50
<62±n/a nM
Citation
 PubChem, PC SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM61037
Synonyms:
2-(1,3-benzothiazol-2-ylsulfanyl)-1-[2-(trifluoromethyl)phenothiazin-10-yl]ethanone | 2-(1,3-benzothiazol-2-ylthio)-1-[2-(trifluoromethyl)-10-phenothiazinyl]ethanone | 2-(1,3-benzothiazol-2-ylthio)-1-[2-(trifluoromethyl)phenothiazin-10-yl]ethanone | 2-(Benzothiazol-2-ylsulfanyl)-1-(2-trifluoromethyl-phenothiazin-10-yl)-ethanone | MLS000549754 | SMR000176186 | cid_1724914
Type:
Small organic molecule
Emp. Form.:
C22H13F3N2OS3
Mol. Mass.:
474.542
SMILES:
FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)CSc3nc4ccccc4s3)c2c1
Structure:
Search PDB for entries with ligand similarity: