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Target
ATP-dependent molecular chaperone HSP82
Ligand
BDBM68338
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90
EC50
63110±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90 PubChem Bioassay (2010)[AID] 
Target
Name:
ATP-dependent molecular chaperone HSP82
Synonyms:
heat shock protein 90
Type:
Enzyme Catalytic Domain
Mol. Mass.:
80784.12
Organism:
Candida albicans
Description:
gi_994798
Residue:
707
Sequence:
MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLEEVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDPLAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLSFIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSKNIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVEKSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKEIKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTMSSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSNFAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
  
Inhibitor
Name:
BDBM68338
Synonyms:
(2Z)-2-(phenylmethylene)-4,9-dihydro-3H-carbazol-1-one | (2Z)-2-(phenylmethylidene)-4,9-dihydro-3H-carbazol-1-one | (2Z)-2-benzal-4,9-dihydro-3H-carbazol-1-one | (2Z)-2-benzylidene-4,9-dihydro-3H-carbazol-1-one | BRD-K70731066-001-03-5 | cid_11958790
Type:
Small organic molecule
Emp. Form.:
C19H15NO
Mol. Mass.:
273.3285
SMILES:
O=C1c2[nH]c3ccccc3c2CC\C1=C\c1ccccc1
Structure:
Search PDB for entries with ligand similarity: