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Target
ATP-dependent molecular chaperone HSP82
Ligand
BDBM64598
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90
EC50
10240±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90 PubChem Bioassay (2010)[AID] 
Target
Name:
ATP-dependent molecular chaperone HSP82
Synonyms:
heat shock protein 90
Type:
Enzyme Catalytic Domain
Mol. Mass.:
80784.12
Organism:
Candida albicans
Description:
gi_994798
Residue:
707
Sequence:
MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLEEVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDPLAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLSFIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSKNIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVEKSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKEIKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTMSSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSNFAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
  
Inhibitor
Name:
BDBM64598
Synonyms:
6-bromanyl-3-oxidanyl-2-[3-(trifluoromethyl)phenyl]quinazolin-4-one | 6-bromo-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone | 6-bromo-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4-quinazolinone | 6-bromo-3-hydroxy-2-[3-(trifluoromethyl)phenyl]quinazolin-4-one | MLS000326257 | SMR000170414 | cid_1487353
Type:
Small organic molecule
Emp. Form.:
C15H8BrF3N2O2
Mol. Mass.:
385.135
SMILES:
On1c(nc2ccc(Br)cc2c1=O)-c1cccc(c1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: