Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM68332
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify activators of signal transducer and activator of transcription 1 (STAT1)
EC50
>5569±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify activators of signal transducer and activator of transcription 1 (STAT1): luminescence-based cell-based dose response assay for STAT3 activators PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM68332
Synonyms:
7-(4-fluorophenyl)-5-methyl-3-phenyl-pyrazolo[1,5-a]pyrimidine | 7-(4-fluorophenyl)-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidine | SR-03000000931-1 | cid_42640807
Type:
Small organic molecule
Emp. Form.:
C19H14FN3
Mol. Mass.:
303.333
SMILES:
Cc1cc(-c2ccc(F)cc2)n2ncc(-c3ccccc3)c2n1
Structure:
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