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Target
Krueppel-like factor 5
Ligand
BDBM70192
Substrate
n/a
Meas. Tech.
Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)
IC50
19381±n/a nM
Citation
 PubChem, PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay (2010)[AID] 
Target
Name:
Krueppel-like factor 5
Synonyms:
BTEB2 | CKLF | IKLF | KLF5 | KLF5_HUMAN | Kruppel-like factor 5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50808.71
Organism:
Homo sapiens (Human)
Description:
Q13887
Residue:
457
Sequence:
MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN
  
Inhibitor
Name:
BDBM70192
Synonyms:
3-[4-(4-tert-butylphenyl)-1,3-oxazol-2-yl]-N-pyridin-2-yl-propanamide | 3-[4-(4-tert-butylphenyl)-1,3-oxazol-2-yl]-N-pyridin-2-ylpropanamide | 3-[4-(4-tert-butylphenyl)-2-oxazolyl]-N-(2-pyridinyl)propanamide | 3-[4-(4-tert-butylphenyl)oxazol-2-yl]-N-(2-pyridyl)propionamide | SR-03000001157 | SR-03000001157-1 | cid_44665690
Type:
Small organic molecule
Emp. Form.:
C21H23N3O2
Mol. Mass.:
349.4262
SMILES:
CC(C)(C)c1ccc(cc1)-c1coc(CCC(=O)Nc2ccccn2)n1
Structure:
Search PDB for entries with ligand similarity: