Reaction Details Report a problem with these data
Target
Protein RecA
Ligand
BDBM42934
Substrate
n/a
Meas. Tech.
Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation
EC50
142300±n/a nM
Citation
 PubChem, PC Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation PubChem Bioassay (2010)[AID] 
Target
Name:
Protein RecA
Synonyms:
DNA recombination protein RecA | RECA_MYCTU | recA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
85386.52
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15609874
Residue:
790
Sequence:
MTQTPDREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKCLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAIVWATPDHKVLTEYGWRAAGELRKGDRVAQPRRFDGFGDSAPIPADHARLLGYLIGDGRDGWVGGKTPINFINVQRALIDDVTRIAATLGCAAHPQGRISLAIAHRPGERNGVADLCQQAGIYGKLAWEKTIPNWFFEPDIAADIVGNLLFGLFESDGWVSREQTGALRVGYTTTSEQLAHQIHWLLLRFGVGSTVRDYDPTQKRPSIVNGRRIQSKRQVFEVRISGMDNVTAFAESVPMWGPRGAALIQAIPEATQGRRRGSQATYLAAEMTDAVLNYLDERGVTAQEAAAMIGVASGDPRGGMKQVLGASRLRRDRVQALADALDDKFLHDMLAEELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIGAVVTDDPSNDGVLPAPVDF
  
Inhibitor
Name:
BDBM42934
Synonyms:
2-[3-[(2-fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanyl-1-(4-phenylpiperazin-1-yl)ethanone | 2-[[3-(2-fluorobenzyl)triazolo[4,5-d]pyrimidin-7-yl]thio]-1-(4-phenylpiperazino)ethanone | 2-[[3-[(2-fluorophenyl)methyl]-7-triazolo[4,5-d]pyrimidinyl]thio]-1-(4-phenyl-1-piperazinyl)ethanone | 2-[[3-[(2-fluorophenyl)methyl]-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]sulfanyl]-1-(4-phenylpiperazin-1-yl)ethanone | 3-(2-fluorobenzyl)-7-{[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]thio}-3H-[1,2,3]triazolo[4,5-d]pyrimidine | MLS000094034 | SMR000029649 | cid_3241158
Type:
Small organic molecule
Emp. Form.:
C23H22FN7OS
Mol. Mass.:
463.53
SMILES:
Fc1ccccc1Cn1nnc2c(SCC(=O)N3CCN(CC3)c3ccccc3)ncnc12
Structure:
Search PDB for entries with ligand similarity: