Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM31709
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
7863±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM31709
Synonyms:
4-amino-2-phenyl-isoindoline-1,3-quinone | 4-amino-2-phenylisoindole-1,3-dione | 4-azanyl-2-phenyl-isoindole-1,3-dione | CHEMBL269410 | MLS000104009 | SMR000015725 | cid_3448473
Type:
Small organic molecule
Emp. Form.:
C14H10N2O2
Mol. Mass.:
238.2414
SMILES:
Nc1cccc2C(=O)N(C(=O)c12)c1ccccc1
Structure:
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