Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM50919
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
11141±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM50919
Synonyms:
2-methoxyethyl 4-amino-3-(2-methoxyethyl)-2-sulfanylidene-1,3-thiazole-5-carboxylate | 2-methoxyethyl 4-azanyl-3-(2-methoxyethyl)-2-sulfanylidene-1,3-thiazole-5-carboxylate | 4-amino-3-(2-methoxyethyl)-2-sulfanylidene-5-thiazolecarboxylic acid 2-methoxyethyl ester | 4-amino-3-(2-methoxyethyl)-2-thioxo-4-thiazoline-5-carboxylic acid 2-methoxyethyl ester | MLS000565318 | SMR000152486 | cid_2402693
Type:
Small organic molecule
Emp. Form.:
C10H16N2O4S2
Mol. Mass.:
292.375
SMILES:
COCCOC(=O)c1sc(=S)n(CCOC)c1N
Structure:
Search PDB for entries with ligand similarity: